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:: Volume 7, Issue 3 (In press Autumn 2017) ::
J Fasa Univ Med Sci 2017, 7(3): 0-0 Back to browse issues page
A Comparison of the effect of three-dimensional music with dexamethasone on the carrageenan- induced inflammation in mature male rats
Hosein Sazegar 1, Bahareh Ahmadi 2
1- Departmant of biology, Faculty of Sciences, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran , hoseinsazgar@yahoo.com
2- Departmant of biology, Faculty of Sciences, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran
Abstract:   (145 Views)

Background & Objective: Inflammation is an undesirable condition resulted from the effect of Arachidonic Acid metabolites especially prostaglandins. With regard to the side-effects of chemical anti-inflammatory medicines, this study was done aiming at examining the effect of 3D music on the extent of inflammation.
Materials and methods: In this experimental study, 20 male Wistar rats (200-250 g) were randomly divided into 4 groups of 5 each, including healthy control group, inflammatory control group, inflammatory recipient of 50 ml of carrageenan1%, treated inflammatory with 2 mg per kg body weight dexamethasone and treated inflammatory with three-dimensional music player (8h). Finally, CRP blood test and weight difference between the injected right foot and the left foot were measured. One-way analysis of variance (ANOVA) was used to analyze the data through SPSS software.There was a significant mean difference between groups, using Tukey test at (p <0.05).
Results: CRP levels in treated groups by dexamethasone (10.6±3.24mg/l), and music (16±9.95mg/l), compared to the control group (37.8±5.24mg/l), were significantly decreased, which this decrease was more discernable in treated groups that received dexamethasone. The weight difference between the left and right foot in the treatment group (0.016±0.007g), (0.044±0.044g) compared to the control group (0.154±0.056g), was significantly decreased.
Conclusion: Dexamethasone can remove inflammation and three-dimensional music can reduce inflammation less than dexamethasone in the inflammatory animals.
 

Keywords: 3D music, Dexamethasone, Inflammation, Carrageenan, Rat
Full-Text [PDF 1040 kb]   (40 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2016/08/21 | Accepted: 2017/04/7 | Published: 2017/11/7
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Sazegar H, Ahmadi B. A Comparison of the effect of three-dimensional music with dexamethasone on the carrageenan- induced inflammation in mature male rats. J Fasa Univ Med Sci. 2017; 7 (3)
URL: http://journal.fums.ac.ir/article-1-1082-en.html
Volume 7, Issue 3 (In press Autumn 2017) Back to browse issues page
Journal of Fasa University of Medical Sciences
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