Background & Objective: Osteoporosis is the most common metabolic bone disease, and its complications include loss of teeth and dry mouth. Thus, this study was designed to evaluate the association of osteoporosis with tooth loss and oral dryness feeling in women with osteoporosis.
 
Materials & Methods: This case-control study was performed on 170 women (85 with osteoporosis and 85 without osteoporosis) referring to the bone densitometry center in the city of Fasa. Data were collected using a valid questionnaire including standard questionnaire of dry mouth and demographic variables, also a clinical examination was carried out for determine the number of missing teeth. The data collected was analyzed by SPSS 22 software. P <0/05 was considered as significant level.
Results: The findings of this study showed that there were significant relationship between osteoporosis and oral dryness feeling (p<0.001). But no significant difference was found between the two groups regarding average number of teeth missing (p=0.09). Also significant was relationship between age and the number of missing teeth (p=0/02), but no significant difference was found between other demographic information among other information regarding the number of missing teeth and oral dryness feeling.
Conclusions: The results showed that in women with osteoporosis, there is a oral dryness feeling. The age can be considered risk factors for tooth loss so that more number of missing teeth with age, but osteoporosis cannot be considered risk factors for tooth loss.