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:: Volume 2, Issue 4 (Winter 2013) ::
J Fasa Univ Med Sci 2013, 2(4): 254-258 Back to browse issues page
Phenotypical Evaluation of Multi-Drug Resistant Acinetobacter Baumannii
Somayyeh Jafari, Sohrab Najafipour 1, Mohammad Kargar, Abbas Abdollahi, Jalal Mardaneh, Mehdi Fasihy Ramandy, Sara Abdollahi Kheirabadi, Ali Moravej
1- , sohrabnajafipour@yahoo.com
Abstract:   (24343 Views)

Background & Objective: Resistance patterns among nosocomial bacterial pathogens in hospitals may vary widely from country to country at any given point and within the same country over time. Acinetobacter baumannii is one of the most important bacteria that cause hospital-acquired infections. Therefore, surveillance of the antibiotic resistance of Acinetobacter baumannii is necessary, especially in our country, where there is death of relevant data.

 

Materials & Methods: This cross-sectional-descriptive study was performed on 63 MDR isolates of acinetobacter baumannii isolated from patients in Fars province hospitals. After acinetobacter baumannii diagnosis with bacteriological standard tests , we determined their susceptibility to the following antibiotics via the antibiogram method (disk diffusion): cefoxitine polymixin B nalidixic acid meropenem tobramycin imipenem trimethoprim sulphametoxazole ampicilin-sulbactam azteronam rifampicin ceftazidim gentamycin cefotaxim piperacillin ciprofloxacin streptomycin amikacin and polymixin B. Minimum inhibitory concentration (MIC ( for imipenem and ciprofloxacin against acinetobacter baumannii isolates was determined using the serial dilution method according to the CLSI guideline. 

  

Results: The percentage of acinetobacter baumannii isolates that were resistant to ciprofloxacin, imipenem, and meropenem in the serial dilution method was 77.7%, 40.9%, and 60%, respectively.

 

Conclusion: High antimicrobial resistance in acinetobacter baumannii species was observed in the present study therefore, it is necessary to implement some approaches for the prevention of bacterial spread.

Keywords: Acinetobacter, Antibiotic resistance, MIC, Imipenem, Ciprofloxacin, Meropenem.
Full-Text [PDF 587 kb]   (7745 Downloads)    
Type of Study: Research | Subject: Pharmacology
Received: 2013/03/13 | Accepted: 2013/09/14 | Published: 2013/09/14
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Jafari S, Najafipour S, Kargar M, Abdollahi A, Mardaneh J, Fasihy Ramandy M, et al . Phenotypical Evaluation of Multi-Drug Resistant Acinetobacter Baumannii. J Fasa Univ Med Sci. 2013; 2 (4) :254-258
URL: http://journal.fums.ac.ir/article-1-148-en.html


Volume 2, Issue 4 (Winter 2013) Back to browse issues page
Journal of Fasa University of Medical Sciences
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