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:: Volume 3, Issue 1 (Spring 2013) ::
J Fasa Univ Med Sci 2013, 3(1): 56-62 Back to browse issues page
The Effects of Hydroalcoholic Extract of Matricaria Recutita on the Hormonal Pituitary-Testis Axis and Testis Tissue Changes of Mature Male Rats
Laili Hatami 1, Jasem Estakhr
1- , hatlail@yahoo.co.uk
Abstract:   (32921 Views)

Background & Objectives: Matricaria recutita is one of the most ancient and well- known medicinal plants, and its role in the treatment of a wide range of diseases has been studied . The purpose of this study was to investigate the effect of Matricaria recutita on spermatogenesis and the pituitary-gonadal axis in male adult rats.

 

Materials & Methods: In this experimental study, the animals were divided into two groups: the control group, which received 1 ml of distilled water orally, and the experimental group, which received 100 mg/kg of Matricaria recutita extract via gavage feeding once daily for an 8-week period. After the treatment period, several fertility indices such as the weight of the reproductive organs, sperm count, sperm motility and vitality, and testis histological changes as well as blood serum levels of testosterone, estrogen, FSH, and LH were measured.

 

Results: Our statistical analysis showed a significant increase in the weight of the reproductive organs, sperm count, and blood testosterone in the group which received 100 mg/kg of Matricaria recutita hydroalcholic extract .

 

Conclusion: The results of this study demonstrated that hydroalcholic extract of Matricaria recutita could increase the function of the hormonal pituitary-testis axis and spermatogenesis in male rats.

 

Keywords: Matricaria recutita, LH, FSH, Testosterone, Spermatogenesis, Rat
Full-Text [PDF 752 kb]   (5138 Downloads)    
Type of Study: Research | Subject: Pharmaceutical Plants
Received: 2012/10/28 | Accepted: 2013/02/17 | Published: 2013/09/14
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Hatami L, Estakhr J. The Effects of Hydroalcoholic Extract of Matricaria Recutita on the Hormonal Pituitary-Testis Axis and Testis Tissue Changes of Mature Male Rats. J Fasa Univ Med Sci. 2013; 3 (1) :56-62
URL: http://journal.fums.ac.ir/article-1-211-en.html


Volume 3, Issue 1 (Spring 2013) Back to browse issues page
Journal of Fasa University of Medical Sciences
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