[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Submit :: Contact Us ::
:: Volume 3, Issue 1 (Spring 2013) ::
J Fasa Univ Med Sci 2013, 3(1): 9-17 Back to browse issues page
Review of Metabolism, Transport and Role of Serotonin in the Body and the Relation between Serotonin and Diseases
Fatemeh Sholehvar 1, Mohammad Ali Takhshid, Maryam Rafiei
1- , shoalehvar@yahoo.com
Abstract:   (36296 Views)

Serotonin (5-hydroxytriptamine), one of the most important neurotransmitters, is synthesized from amino acid L-tryptophan in some neurons located in the central nervous system and intestine enterochromaffin cells . The role of this neurotransmitter is important and involves control of sexual behaviors, morality, sleep, pain, appetite, aggression, cardiovascular function and regulation of gut function. Serotonin is stored in cells by serotonin transporter and after release, it binds to its specific receptors so as to perform its function, which is neuronal stimulation. There is a relationship between serotonin concentration changes, serotonin transporter gene alleles, and serotonin receptors and some diseases consequently, using some drugs which are effective on these factors could be useful in the treatment of these diseases.

Keywords: Serotonin, Neurotransmitter, Transporter, Receptor, Allele
Full-Text [PDF 979 kb]   (16906 Downloads)    
Type of Study: Review | Subject: Biochemistry
Received: 2012/09/26 | Accepted: 2012/12/25 | Published: 2013/09/14
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sholehvar F, Takhshid M A, Rafiei M. Review of Metabolism, Transport and Role of Serotonin in the Body and the Relation between Serotonin and Diseases. J Fasa Univ Med Sci. 2013; 3 (1) :9-17
URL: http://journal.fums.ac.ir/article-1-220-en.html


Volume 3, Issue 1 (Spring 2013) Back to browse issues page
Journal of Fasa University of Medical Sciences
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4006