[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Submit :: Contact Us ::
:: Volume 7, Issue 1 (Spring 2017) ::
J Fasa Univ Med Sci 2017, 7(1): 53-59 Back to browse issues page
In vivo screening antifungal activity of methanolic extract of Protoparmeliopsis muralis against Aspergillus flavus
Somaye Rashki 1, Tahereh Valadbeigi 2
1- Department of Biology, Faculty of Basic Science Ilam University, Ilam, Iran , somaye_rashki@yahoo.com
2- Department of Biology, Faculty of Basic Science Ilam University, Ilam, Iran
Abstract:   (1213 Views)

Background & Objective: Lichens are the result of the symbiosis of fungi and algae or a cyanobacterium. Various biological activities of some lichen and their components such as: antifungal, anti-bacterial, anti-tumor, anti-inflammatory, antiprotozoal substances are known. In the present study, antifungal activity of methanolic extract of Protoparmeliopsis muralis against Aspergillus flavus is investigated on rats.

Materials & Methods: 500 g of Protoparmeliopsis muralis was collected from KaneGonbad mountains in Ilam province, the methanol extract was prepared by soxhle. In order to determine the antifungal activity in in vivo conditions, a wound was created and infected with Aspergillus flavus. Having infected the wound, the researchers divided the rats into 4 subgroups: negative control group, treated with Kotrimoksazol, %5 ointment extract methanolic P. muralis, and with %10 ointment extract methanolic P. muralis. Treatment continued until complete healing of the wound. Finally, the percentage of wound healing was calculated.

Results: The result of the present study demonstrated that methanolic extract of P. muralis decreased the area of wound in the treatment group compared to the control group.

Conclusion: The antifungal and antioxidant activity of the extract of Protoparmeliopsis muralis accelerated the wound healing process.

Keywords: Aspergillus flavus, fungi, Protoparmeliopsis muralis, wound, extract
Full-Text [PDF 1283 kb]   (263 Downloads)    
Type of Study: Research | Subject: Mycology
Received: 2016/05/15 | Accepted: 2016/12/25 | Published: 2017/06/6
Send email to the article author

Add your comments about this article
Your username or Email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rashki S, Valadbeigi T. In vivo screening antifungal activity of methanolic extract of Protoparmeliopsis muralis against Aspergillus flavus. J Fasa Univ Med Sci. 2017; 7 (1) :53-59
URL: http://journal.fums.ac.ir/article-1-796-en.html
Volume 7, Issue 1 (Spring 2017) Back to browse issues page
Journal of Fasa University of Medical Sciences
Persian site map - English site map - Created in 0.052 seconds with 791 queries by yektaweb 3531