Volume 6, Issue 2 (8-2016)                   JABS 2016, 6(2): 133-137 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hosseini M, Khoshnoud R, Gholamzadeh S, Naseri G, Tarian T, Malekpour A et al . A Case Report of Suicide with Chloroquine Overdose and Review of Literature. JABS 2016; 6 (2) :133-137
URL: http://jabs.fums.ac.ir/article-1-980-en.html
1- Legal Medicine Research Center, Legal Medicine Organization of Iran, Tehran, Iran
2- Legal Medicine Research Center, Legal Medicine Organization of Iran, Tehran, Iran , saeedghmail@yahoo.com
Abstract:   (14401 Views)

Background & Objective: Suicide is considered as the tenth cause of death worldwide. There are several suicide reports consist in the use of certain unusual drugs, such as chloroquine.

Case report: The cadaver of a 25-year-old single woman was found dead in her home and with suspect to using toxins or drugs was brought to Fars Province Forensic administration. She had history of psychiatric problems for which had referred to psychologist several times.

Results: After the autopsy, there was no observation of pathologic lesions in her samples of liver, kidney, or heart. In bile samples, using Thin Layer Chromatography (TLC) and High Performance Liquid Chromatography (HPLC) methods, chloroquine was detected. In visceral and gut samples, chloroquine was found using TLC as +4 reactions and it was confirmed by HPLC and Gas Chromatography Mass Spectrometry (GC-MS). After examining all the aspects, eventually chloroquine overdose and its complications was determined as the cause of the death.

Conclusion: Due to the high incidence of suicide in depressed patients and according to family and previous positive experience, preventive strategies based on the recognition and the treatment of depressed patients and also teaching the families to diagnose the illness in addition to the limitation of the free access to chloroquine and similar drugs is suggested to reduce overdose complications or suicide.

Full-Text [PDF 826 kb]   (56886 Downloads)    
Type of Study: case report | Subject: Forensic Medicine
Received: 2016/01/7 | Accepted: 2016/05/14 | Published: 2016/09/10

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Advanced Biomedical Sciences

Designed & Developed by: Yektaweb

Creative Commons License
This work is licensed under a Creative Commons — Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)