:: Volume 8, Issue 3 ( Autumn 2018) ::
JABS 2018, 8(3): 918-928 Back to browse issues page
Investigating the relationship between Dietary total antioxidant capacity and depression and anxiety in Iranian adults
Mohammad Mousavi 1, Alireza Milajerdi2 , Ammar Hassanzadeh Keshteli3 , Ahmad Esmaillzadeh4 , Hamid Afshar5, Peyman Adibi5
1- Tehran University of Medical Sciences , smmousavi@razi.tums.ac.ir
2- Tehran University of Medical Sciences
3- Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
4- Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
5- Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences
Abstract:   (3443 Views)
Background & Objective: Although several studies are available linking individual dietary antioxidants to the risk of psychological disorders, data about the association of dietary total antioxidant capacity (TAC) with depression and anxiety are scarce. This study was conducted to investigate the association between dietary TAC and odds of depression and anxiety among Iranian adults.
Material & Methods: In this cross-sectional study, dietary intakes of 3297 apparently healthy adults in Isfahan province, Iran, were assessed using a validated detailed food frequency questionnaire. Dietary TAC was estimated using the ferric-reducing antioxidant power (FRAP) international databases. Depression and anxiety were assessed using a validated Persian translated version of Hospital Anxiety and Depression Scale (HADS) questionnaire. Having the scores 0-7 in either subscales was considered as “normal” and the scores of 8 or more as the presence of depression or anxiety.
Results: Overall, 28.6% (n= 943) of study participants were depressed or at the borderline level, and 13.6% (n= 448) had anxiety or were at the borderline level. After controlling for potential confounders, including dietary intakes of omega-3 fatty acids, we found that those in the top quintile of dietary TAC were 43% less likely to be depressed than those in the bottom category (OR: 0.57; 95% CI: 0.40-0.82, Ptrend= 0.001). Regarding anxiety, there was a significant inverse association between dietary TAC and anxiety comparing extreme quintiles (OR: 0.62; 95% CI: 0.39-0.99, Ptrend= 0.06).
Conclusion: A significant inverse association between dietary TAC and odds of depression and anxiety was found among adults. Further prospective studies are required to confirm these findings.
Keywords: Anxiety, Depression, Dietary total antioxidant capacity, Iran, Mood
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Type of Study: Research | Subject: Nutrition
Received: 2017/12/14 | Accepted: 2018/07/6 | Published: 2018/12/22


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Volume 8, Issue 3 ( Autumn 2018) Back to browse issues page