:: Volume 9, Issue 1 (Spring 2019) ::
JABS 2019, 9(1): 1187-1199 Back to browse issues page
The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
Parisa Fouman Ajirloo1 , Arezo Zaree1 , Saeid Ghorbian 2
1- Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran
2- Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran , ghorbian20@yahoo.com
Abstract:   (2565 Views)
Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this research was to indicate that there are many long non-coding RNAs with over 200 nucleotides length found in the human genome, which showed a significant role in the pathogenesis of prostate cancer. 
Conclusion: The role of LncRNAs as tumor suppressors or oncogenes has been demonstrated in several types of cancers, including prostate cancer. Recent investigations have disclosed that LncRNAs transcripts play a pivotal role in the tumorigenesis.
 


 
Keywords: prostate cancer, long non-coding RNA, LncRNA
Full-Text [PDF 1244 kb]   (1868 Downloads)    
Type of Study: Review | Subject: Oncology
Received: 2018/08/17 | Accepted: 2019/01/7 | Published: 2019/06/8


XML   Persian Abstract   Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 9, Issue 1 (Spring 2019) Back to browse issues page