TY - JOUR JF - JABS JO - JABS VL - 9 IS - 3 PY - 2019 Y1 - 2019/9/01 TI - Angiogenesis and Metastasis with a Therapeutic Approach: A Review TT - مروری بر رگ زایی و نقش آن در متاستاز به همراه اهداف درمانی N2 - Angiogenesis is a process in which new blood vessels produced from old vessels and this process plays an important role in the natural processes in body. Also, angiogenesis in tumor cells leads to further growth of these cells and leads to their metastasis. This process involves migration, proliferation and differentiation of endothelial cells. One of the new ideas that attracted the attention of scientists is to inhibit the angiogenesis process in cancer patients. Scientists are hoping that this method leading to a tumor cells therapy. The purpose of this study was to review the role of angiogenesis in metastasis of tumor cells with a therapeutic approach. SP - 1525 EP - 1533 AU - Rostami, Dariush AU - abdollahi, elahe AU - taghizadeh, hassan AU - gheibi hayat, sayed mohammad AU - taghizadeh, eskandar AD - Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad Iran KW - Angiogenesis KW - Tumor KW - Metastasis UR - http://jabs.fums.ac.ir/article-1-1594-en.html ER -