Journal of Advanced Biomedical Sciences
مجله علوم زیست پزشکی پیشرفته
JABS
Medical Sciences
http://jabs.fums.ac.ir
1
admin
2228-5105
2783-1523
8
7
14
8888
13
en
jalali
1400
2
1
gregorian
2021
5
1
11
2
online
1
fulltext
en
نانوذرات پلی لاکتیک اسید: نویدی برای مبارزه با سرطان
Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers
نانوتکنولوژی پزشکی
Nanomedicine
مروری
Review
<div style="text-align: justify;">Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid)(PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.<br>
</div>
Poly (Lactic Acid), Polymeric Nanoparticle, Cancer Treatment, Drug Deliver, Gene Delivery, Tumor Cell
3791
3814
http://jabs.fums.ac.ir/browse.php?a_code=A-10-2559-1&slc_lang=en&sid=1
Farnaz
Fattahi
فرنازالسادات
فتاحی
fattahi_farnaz@yahoo.com
100319475328460026342
100319475328460026342
Yes
Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran
گروه مهندسی نساجی، دانشگاه صنعتی اصفهان، اصفهان، ایران
Tahereh
Zamani
طاهره
زمانی
zamani.tahere@iran.ir
100319475328460026343
100319475328460026343
No
The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
مرکز تحقیقات ژنتیک، دانشگاه علوم بهزیستی و توانبخشی، تهران، ایران