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:: Volume 2, Issue 4 (Winter 2013) ::
J Fasa Univ Med Sci 2013, 2(4): 273-278 Back to browse issues page
Evaluation of Drug Resistance Pattern of Escherichia coli Strains Isolated from Fasa Vali-e-Asr Hospital Patients
Sara Abdollahi Kheirabadi, Sohrab Najafipour 1, Farshid Kafilzadeh, Abbas Abdollahi, Somayeh Jafari, Ali Moravej
1- , sohrabnajafipour@yahoo.com
Abstract:   (23167 Views)

Background & Objective: Antibiotic resistance due to the widespread use of antibiotics is one of the major causes of failure in antibiotic treatment. The aim of this study was to investigate the rates of antibiotic resistance among Escherichia coli isolates from Fasa Vali-e-Asr Hospital patients. 

 

Materials & Methods : In total, 234 isolates of Escherichia coli strains, obtained from inpatients and outpatients, were studied. The identity of the isolated strains was confirmed by bacteriologic methods. T he drug sensitivity definition test to 17 antibiotics was done via the disk diffusion antibiogram method. Minimum inhibitory concentration (MIC) of the resistant isolates to Ciprofloxacin and Imipenem was measured using the s erial dilution method according to the CLSI standards.

 

Results : The resistance rates of the isolates to Ciprofloxacin and Imipenem by disk diffusion antibiogram method were 22.65% and 11.11% and by serial dilution method were 19.66 % and 9.4% of all the isolates, respectively.

 

Conclusion: These results show higher resistance of Escherichia coli to Ciprofloxacin and Imipenem as compared to the results in previous studies. Further investigation will shed light on how to more effectively battle antibiotic resistance of virulent microorganisms.

Keywords: Escherichia coli, Antibiotic resistance, Minimum inhibitory concentration
Full-Text [PDF 597 kb]   (10486 Downloads)    
Type of Study: Research | Subject: Microbiology
Received: 2013/03/12 | Accepted: 2013/09/14 | Published: 2013/09/14
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Abdollahi Kheirabadi S, Najafipour S, Kafilzadeh F, Abdollahi A, Jafari S, Moravej A. Evaluation of Drug Resistance Pattern of Escherichia coli Strains Isolated from Fasa Vali-e-Asr Hospital Patients . J Fasa Univ Med Sci. 2013; 2 (4) :273-278
URL: http://journal.fums.ac.ir/article-1-143-en.html


Volume 2, Issue 4 (Winter 2013) Back to browse issues page
Journal of Fasa University of Medical Sciences
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