Journal of Advanced Biomedical Sciences

Background & Objective: Burn injuries are one of the health hazards of today society. Considering the use of silver sulphadiazine in clinics and mastic gum-ghee mixture in some regions of Iran for burn recovery, this study was designed to compare the effect of mastic gum-ghee mixture and silver sulfasalazine ointment 1% in treating second degree burns.
Materials & Methods: This experimental single blind study was performed after anesthetizing 10-rat groups with sodium thiopental (Intra Peritoneal Injection). During the four -week treatment with silver sulfadiazine ointment1%, Vaseline, pure ghee, or mastic gum-Vaseline mixture in three dosages (50,100. and 200 mg mastic gum in Vaseline in gram) and mastic gum-ghee in dosages of 50,100, and 200 mg mastic gum in ghee in gram, the effects of this substances on the remission of the ulcers were evaluated qualitatively and clinically.

Results: In the first two weeks of treatment after burn, most groups had almost similar trend of remission. But in the next two weeks of treatment, the degree of recovery changed in different groups. The silver sulfadiazine group, the mixture of mastic gum- Vaseline (200mg/ g) and Vaseline showed the highest improvement, respectively (according to the dermatologist opinion).

Conclusion: According to this  study, it is suggested  not to use mastic gum-ghee mixture for second degree burns. We recommend that  sulfadiazine ointment 1% is the better choice for the recovery of burn injuries.