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:: Volume 4, Issue 4 (Winter 2015) ::
J Fasa Univ Med Sci 2015, 4(4): 475-484 Back to browse issues page
Therapeutic Effects of Topical Minoxidil or Rosemary and the Combination of Both on the treatment of Alopecia areata
Mohammad Hossein Lohrasb1, Mahshid Ghodrat2, Mohammad Hassan Meshkibaf 3
1- Department of Dermatology, Fasa University of Medical Sciences, Fasa, Iran.
2- Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
3- Department of Biochemistry, Fasa University of Medical Sciences, Fasa, Iran , meshkibaf2000@gmail.com
Abstract:   (9426 Views)

Background & Objectives: Considering the prevalence of Alopecia areata, , failure of treatment, and the unknown pathogenesis of this illness, a comparative study was performed by using topical Minoxidil 2% and topical rosemary solution alone and in combination to treatment this disease.

Materials & Methods: This study is a clinical trial performed on 200 patients with Alopecia areata referring to Hamzeh clinic of Fasa during the years 2012 and 2013. They were divided into four groups by random permutation, each group contained 50 patients. Group one received the combination of topical Minoxidil 2% and topical rosemary, group two received only topical Minoxidil 2% solution, group three received only topical rosemary solution and the fourth group, the case-control group, did not receive any medication and were just advised to rub the site of the disease for the same period of time. The patients were under observation for one year.

Results: The Results of this investigation showed that the best remissions after treatments were as follow (respectively): combination of topical Minoxidil 2% and topical rosemary (27 patient=54 %), Minoxidil 2% solution (23 patients =46%), rosemary solution (21 patients =42%), and case- control group (9 patients =18%). These results showed that despite better response to the combination of rosemary and Minoxidil solutions in comparison to the two other treated groups, the changes were minimal and statistically insignificant (P-value =0.0411).

Conclusion: Using the combination of both rosemary and Minoxidil is more effective than the individual one on treatment of Alopecia areata.

Keywords: Alopecia areata, Rosemary, Minoxidil
Full-Text [PDF 1237 kb]   (2516 Downloads)    
Type of Study: Research | Subject: Dermatology
Received: 2014/05/25 | Accepted: 2014/09/20 | Published: 2015/03/19
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Lohrasb M H, Ghodrat M, Meshkibaf M H. Therapeutic Effects of Topical Minoxidil or Rosemary and the Combination of Both on the treatment of Alopecia areata. J Fasa Univ Med Sci. 2015; 4 (4) :475-484
URL: http://journal.fums.ac.ir/article-1-568-en.html


Volume 4, Issue 4 (Winter 2015) Back to browse issues page
Journal of Fasa University of Medical Sciences
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