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Angiogenesis and Metastasis with a Therapeutic Approach: A Review
Dariush Rostami1 , Elahe Abdollahi2 , Hassan Taghizadeh3 , Sayed mohammad Gheibi hayat4 , Eskandar Taghizadeh 5
1- Department of Anesthesiology, Faculty of Paramedicine, Zabol University of Medical Sciences, Zabol, Iran
2- Department of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran
3- Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasouj, Iran
4- Department of Medical Genetics, Faculty of Medicine, Yazd University of Medical Sciences, Yazd, Iran
5- Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad Iran , eskandar.taghizadeh@yahoo.com
Abstract:   (151 Views)

Angiogenesis is a process in which new blood vessels produced from old vessels and this process plays an important role in the natural processes in body. Also, angiogenesis in tumor cells leads to further growth of these cells and leads to their metastasis. This process involves migration, proliferation and differentiation of endothelial cells. One of the new ideas that attracted the attention of scientists is to inhibit the angiogenesis process in cancer patients. Scientists are hoping that this method leading to a tumor cells therapy. The purpose of this study was to review the role of angiogenesis in metastasis of tumor cells with a therapeutic approach.

Keywords: Angiogenesis, Tumor, Metastasis
     
Type of Study: Review | Subject: Medical Genetics
Received: 2017/11/21 | Accepted: 2018/07/7
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