[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Submit :: Contact Us ::
:: Spring(In press) ::
Back to the articles list Back to browse issues page
The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
Parisa Fouman Ajirloo1 , Arezo Zaree1 , Saeid Ghorbian 2
1- Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran
2- Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran , ghorbian20@yahoo.com
Abstract:   (358 Views)
Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this research was to indicate that there are many long non-coding RNAs with over 200 nucleotides length found in the human genome, which showed a significant role in the pathogenesis of prostate cancer. 
Conclusion: The role of LncRNAs as tumor suppressors or oncogenes has been demonstrated in several types of cancers, including prostate cancer. Recent investigations have disclosed that LncRNAs transcripts play a pivotal role in the tumorigenesis.
 


 
Keywords: prostate cancer, long non-coding RNA, LncRNA
     
Type of Study: Review | Subject: Oncology
Received: 2018/08/17 | Accepted: 2019/01/7
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code


XML   Persian Abstract   Print



Back to the articles list Back to browse issues page
Journal of Fasa University of Medical Sciences
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 3877