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:: Volume 5, Number 3 (Autumn 2015) ::
J Fasa Univ Med Sci 2015, 5(3): 306-322 Back to browse issues page
An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells
Zahra Barzkar1, Mohammadhosein Karimi2, Zohre Makoolati3, Gholamreza Kaka4, Majid Naghdi 5
1- Noncommunicable diseases research center, Fasa University of Medical Sciences, Fasa, Iran
2- Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3- Department of Anatomical sciences, Fasa University of Medical Sciences, Fasa, Iran
4- Neuroscience research centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
5- Department of Anatomical sciences, Fasa University of Medical Sciences, Fasa, Iran , majidnaghdi@yahoo.com
Abstract:   (3829 Views)

In the last 15 years, there has been a significant increase in the number of researchers interested in studying Mesenchymal Stem Cells (MSCs). MSCs are self-renewing, heterogenic, and multipotent cells that have multi-lineage potential to differentiate not only in to cell types of mesodermal origin but also other various cell lineage MSCs migrate to inflammatory tissues and apply immunosuppressive effects. The usages of these cells as diagnostic tool, secretor of some growth factors and cytokines, gene expresser of engineered cells, and other characteristics such as relatively easy preparation and proliferation, add to the attraction of these cells. Scientists suggest that the transplantation of these cells is a proper alternative for treatment of some incurable illnesses of bone, heart, skin, and liver such as diabetes. However, these kinds of treatment, not clearly associated with the definitive remedial results, are going on in an additive manner. Introducing stem cells with their miracle properties as a predictive precipitance and their curative potential in the recent years, led to many questions, concerns, and expectations regarding this newly proposed therapeutic method. Nowadays, knowing the true extent of the curative effect of these cells, especially in some tissues more clearly reduces concerns and makes expectations more rational like other treatments. 

Keywords: Mesenchymal stem cells, Studies, Facts, Therapeutic ability
Full-Text [PDF 813 kb]   (2103 Downloads)    
Type of Study: Review | Subject: Developmental Biology
Received: 2015/02/15 | Accepted: 2015/06/6 | Published: 2015/11/14
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Barzkar Z, Karimi M, Makoolati Z, Kaka G, Naghdi M. An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells. J Fasa Univ Med Sci. 2015; 5 (3) :306-322
URL: http://journal.fums.ac.ir/article-1-756-en.html
Volume 5, Number 3 (Autumn 2015) Back to browse issues page
Journal of Fasa University of Medical Sciences
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