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:: Volume 5, Number 4 (Winter 2016) ::
J Fasa Univ Med Sci 2016, 5(4): 444-448 Back to browse issues page
The orbital and sinonasal hemangiopericytoma, 2 case reports:
Maryam Maghbol 1, Mohammadjavad ashraf2, Negar Azarpira3
1- Pathology department of fassa University of Medical Sciences, fassa, Iran. , maghbol.maryam@yahoo.com
2- Pathology department of Shiraz University of Medical Sciences, Shiraz, Iran.
3- Transplant research center, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract:   (2935 Views)

Background & objective: Hemangiopericytoma is an uncommon vascular tumor derived from the pericytes of Zimmermann. . The most common location of the tumor is pelvic retroperitoneum and musculoskeletal system of the lower extremities. It is rarely seen in the head and neck area. In addition, only 0.8% to 3% of all orbital tumors and less than 5 % of primary sinonasal tumors are primary hemangiopericytoma, which demonstrates that the orbital and sinonasal cavities are rare locations for this tumor.

Case: 2 cases of primary orbital and sinonasal hemangiopericytoma that were successfully treated through surgery were reported.

Conclusion: Hemangiopericytoma is an uncommon vascular tumor which has a potentially malignant behavior. Histopathologic features alone do not predict the biologic behavior of the tumor but the increased cellularity, necrosis, hemorrhage and more than 4 mitotic figures per 10 high power field, may elicit a diagnosis of malignant hemangiopericytoma . The local recurrence and the distant metastasis might also occur with an incomplete excision.  The lung, bone and liver are the most common sites of distant metastasis. Thus, the long-term follow-up is recommended after the surgical removal of the tumor.

Keywords: Orbital and sinonasal hemangiopericytoma, Proptosis, Epistaxis
Full-Text [PDF 990 kb]   (1167 Downloads)    
Type of Study: case report | Subject: Pathology
Received: 2015/09/19 | Accepted: 2015/12/6 | Published: 2016/03/7
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Maghbol M, ashraf M, Azarpira N. The orbital and sinonasal hemangiopericytoma, 2 case reports:. J Fasa Univ Med Sci. 2016; 5 (4) :444-448
URL: http://journal.fums.ac.ir/article-1-758-en.html
Volume 5, Number 4 (Winter 2016) Back to browse issues page
Journal of Fasa University of Medical Sciences
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