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Gholamabbas Valizadeh, Mostafa Bizhani, Ehsan Bahramali, Seyyed Amin Kouhpayeh,
Volume 4, Issue 1 (5-2014)
Abstract

 

Background & Objective: Choosing antihypertensive as a drug for treating hypertension is the most important part of its treatment. The present study was done in investigating the consistancy rate of hypertension treatment through Guide Line JNC-7 in patients who were referred to health centers and health houses of Fasa University of Medical Sciences in 2012.

  

 Materials & Methods: In this cross- sectional study, the non-random sample of population was consisted of 200 patients who were suffering from hypertension. The questionnaire contained both demographic information and the use of anti-hypertension medication based on guide line (JNC-7 (. After the confirmation approval of content validity and reliability of the questionnaire, the data and the descriptive statistics were analyzed through SPSS-15 software.

  

Results: 60 ٪ of the patients were in the first stage of hypertension and 40 percent of them were in the second one. Beta blockers were the most common prescribed drugs which were used among the first stage patients. However, ACEI and Diuretics (Thiazides) were the commonly prescribed drugs for the second stage hypertension patients.

 

Patients who had diabetes and heart failure were used Beta- blocker drugs which was not in line with the Guide line JNC-7.

  

Conclusions: The treatment of hypertension in patients was not in consistence with guideline JNC-7. It is recommended to organize training classes for doctors to inform patients about the better way of treating this problem.

 

 

 

 
Mostafa Bijani, Abbas Valizadeh, Amenh Sayari , Babak Samizadeh ,
Volume 4, Issue 4 (12-2014)
Abstract

 

Background & Objective: Coronary angiography has become the largest interventional diagnostic test in recent years. As it has had large effects on anxiety and satisfaction of patients in treatment and care the objective of the present study is to survey the reasons for which the patients, referring to cardiac ward of Valiasr hospital in Fasa, refuse to undergo coronary angiography.

  

Materials & Methods: In this cross-sectional study, 60 individuals candidate for coronary angiography were selected. The samples were selected via census. The tool for collecting the data was a researcher-made questionnaire. The data were analyzed by SPSS-15 software, descriptive statistics, Mann-Whitney test, and Kruskal- Wallis test.

  

Results: The mean age of the samples was 58/9±12/8 years. Financial problems, fear and anxiety, lack of awareness, and lack of confidence in the physician’s diagnosis were the most important factors. The effect of fear has been reported more in women compared to men for refusing coronary angiography (p=.037).

  

Conclusion: According to the above results, financial problems, fear and anxiety, lack of awareness, and lack of confidence in the physician’s diagnosis are the factors effective in accepting coronary angiography. Therefore, more contrivances are needed to eliminate these effective factors in order to prepare cardiac patients, who are candidate for coronary angiography, a tranquility to accept and to perform angiography.

 

 

 
Nahid Bijeh, Samaneh Farahati, Zahra Sarlak, Roghaieh Shad, Babak Hooshmand Moghadam,
Volume 9, Issue 4 (11-2019)
Abstract

Background & Objective: At present, the prevalence of hypertension is growing and one of the contributing factors in the occurrence and development of hypertension and atherosclerosis is impaired renin–angiotensin system which in this system endothelium angiotensin converting enzyme is the main enzyme. The aim of this study was to investigate the effect of eight weeks aerobic training on serum angiotensin converting enzyme and lipid profile in inactive overweight women.
Materials & Methods: In this semi-experimental study, twenty healthy women (20-30 years old) with BMI>25 kg/m 2 were randomly divided into training group (n = 10) and control group (n = 10). The training group performed aerobic exercise for eight weeks, three sessions per week with 55-75% of maximum heart rate. The duration of each training session was increased from 40 to 60 minutes gradually. 48 hours before and after aerobic training program, anthropometric measurements, VO2max, lipid profile, angiotensin-converting enzyme (ACE) of all subjects were measured. Data were analyzed with paired t-independent test and t-student test at a significance level of P<0.05.
Results: Results showed that eight weeks of aerobic training had a significant effect on weight (p=0/01) and BMI (p=0/01) in training group; While changes in angiotensin converting enzyme (p=0/543) and LDL(p=0/927), HDL(p=0/120), Triglyceride (p=0/788) and Cholesterol (p=0/324) during pre-test and post-test was not significant in between groups.
Conclusion: Eight weeks of training program have improved angiotensin converting enzyme, LDL, HDL, Triglyceride and Cholesterol in women, approximately. And it can be said that regular exercise may probably have a preventive effect on the prohibition of cardiovascular disease in overweight women.
 

 
Mohammad Vahid Jorat, Mohammad Hossein Nikoo, Leila Malekmakan, Maryam Al Sadat Salami, Seyed Mojtaba Kashfipour, Seyed Amir Aslani, Seyed Taghi Heydari, Negar Firouzabadi,
Volume 10, Issue 1 (4-2020)
Abstract

Background & Objectives: In recent years, the rate of implantation of cardiac implantable electronic devices (CIED) has progressively increased, while the rate of device related infections (DRI) was disproportionately higher. To decrease the chance of DRI, we evaluated the effect of two local antibiotic prophylaxis methods during CIED implantation on preventing pocket infection as the most common DRI.
Materials & Methods: This retrospective, multicenter, cohort study included patients who underwent CIED implantation. All patients received intravenous antibiotic one hour prior to operation. Local antibiotic prophylaxis was done for all patients by either of two methods; irrigation of the pocket by Cephalothin, or its injection into the pocket at the end of the procedure via suture line, according to the operator’s preference.
Results: From March 2011 to March 2016, 1003 patients underwent CIED implantation. Pocket irrigation by antibiotic was done for 664 cases and antibiotic injection for 339 cases. Infection rate was 1.6% in all patients; 2.3% in irrigation group vs. 0.3% in injection group (P=0.016). There were not significant differences in lead impedance and pacing threshold trend up to 2 months after devices implantation among the patients with two methods of local antibiotic prophylaxis. (P>0.05)
Conclusion: Local antibiotic injection via the suture line after CIED implantation may increase prophylactic effect of intravenous antibiotic infusion against DRI.
 

Mahdiyeh Nasiri Ivanaki, Sirous Farsi, Hadi Ghaedi,
Volume 11, Issue 1 (3-2021)
Abstract

Background & Objective: The studies of the last two decades have shown that regular training is associated with the reduction of mortality among patients with breast cancer, and has an important role in inhibiting breast cancer progression as well as treatment of the disease. However, the micro-molecular mechanisms involved are not fully understood yet. However, the aim of the present study was to investigate the effect of a high-intensity interval training (HIIT) on the expression of miR-126, miR-296, HGS gene, and VEGF-A protein level in tumor tissue of the mice with breast cancer.  
Materials & Methods: For this purpose, 12 BALB/c mice (6-8 weeks, weight 19 ± 1.05 g), after induction of cancer (MC4-L2 subcutaneous injection into the right side of the mice), were randomly divided into two groups with 6 in each group: HIIT and control. Each session of HIIT group program includes six intervals of three minutes and 20 seconds with an intensity of 85 to 90 percent of VO2max and 1-minute recovery with 30 to 35 percent VO2max intensity between each interval; and the animals were sacrificed 24 hours after the last training session and the expression of miR-126, miR-296, HBS gene and VEGF protein levels in tumor tissues were examined.
Results: The statistical results showed that the implementation of HIIT significantly reduced the expression of miR-296 and subsequently increased the HGS gene expression and led to increased expression levels of miR-126 and decreased levels of VEGF-A protein in the training group compared to the control group (p<0.05).
Conclusion: It seems that HIIT, by suppressing tumor angiogenesis signaling pathways, could be an effective intervention to inhibit the growth of breast tumors.
 

Zeinab Ghorbani, Elham Imani, Saeed Hoseini Teshnizi,
Volume 11, Issue 2 (5-2021)
Abstract

Background & Objective: Hypertension is one of the leading causes of death in the world. Some more effective management of this disease can be achieved by making changes in the lifestyles of patients by self-care education. It is important to use new educational methods to better influence education on people's learning. Therefore, the aim of this study was to investigate the effect of using educational tools appropriate to learning style during self-care training on the lifestyle of hypertensive patients.
Materials & Methods: This quasi-experimental study was performed on 44 patients with hypertension who were divided into four groups of visual, auditory, reading/writing and kinesthetic based on their answers to the VARK learning style questionnaire. Patients' self-care training was conducted in the form of four 60-minute sessions based on the learning style of each group. Before and two months after the intervention, the LSQ lifestyle questionnaire was completed by all patients, and finally, data were analyzed using SPSS ver.21.
Results: According to the results of the present study, the mean score of lifestyle dimensions of all research units at all stages of lifestyle increased significantly after the educational intervention compared to before the intervention, (p< 0.001). Also, the increase in the mean of the total lifestyle score after the intervention compared to the time before it was statistically significant (p<0.001).
Conclusion: Considering the favorable effect of self-care education based on learning style in promoting patients' lifestyle, this educational method can be used as a cheap and practical method in changing the behavior of hypertensive patients.
 

Shahin Dehghani, Mostafa Bijani, Zahra Khiyali, Zhale Zandieh,
Volume 15, Issue 1 (1-2025)
Abstract

Background & Objectives: Acute coronary syndrome (ACS), one of the most common cardiovascular conditions affecting older adults, poses significant health challenges. Illness perception and self-efficacy are widely regarded as key factors in the effective management of cardiovascular diseases. Therefore, this study examined the relationship between illness perception and self-efficacy in older patients diagnosed with ACS in southern Iran.
Materials & Methods:  This cross-sectional study was conducted from September to November 2024 among 164 older patients with ACS in Fasa, southern Iran, using convenience sampling. Data were collected via a demographic questionnaire, the Illness Perception Questionnaire developed by Broadbent et al., and Sullivan's Cardiac Self-Efficacy Scale.
Results: Of the 164 participants, 102 (62.2%) were male and 62 (37.8%) were female. The mean age was 67.21 ± 5.46 years, and the mean duration of illness was 5.67 ± 4.41 years. The mean illness perception score was 45.32 ± 13.94, while the mean self-efficacy score was 28.96 ± 2.41; both scores were categorized as moderate. Pearson’s correlation analysis revealed a significant positive correlation between illness perception and self-efficacy. However, no significant association was observed between demographic variables and either illness perception or self-efficacy.
Conclusion: The study's findings indicate that both illness perception and self-efficacy in older patients with ACS were at moderate levels. Furthermore, a significant, positive correlation was identified between illness perception and self-efficacy. Accordingly, it is recommended that health policymakers and administrators implement strategies aimed at enhancing self-awareness, illness perception, and self-efficacy among this population.


 

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