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:: Volume 6, Number 1 (Spring 2016) ::
J Fasa Univ Med Sci 2016, 6(1): 87-95 Back to browse issues page
Investigating the Effect of Sesamum Indicum Consumption on Biochemichal Parameters in Type 2 Diabetic Patients
Atena Sadat Ghoreishi1, Fahimeh Mohammadian Shahrbabaki1, Navid Toghroli1, Mahmoud Sheikh Fathollahi2, Mohammad Reza Hajizadeh1, Alireza Khoshdel1, Mahdi Mahmoodi 3
1- Clinical Biochemistry Department, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
2- Department of Social Medicine and Occupational Environment Research Center, Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3- Molecular Medicine Research Center, Clinical Biochemistry Department, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran , Mahmoodies@yahoo.com
Abstract:   (2396 Views)

Background & Objectives: Diabetes is one of the most common diseases which is usually seen in modern societies. Due to the increased risk of the disease and its related complications, in addition to the harmless properties of sesame seeds, this research was aimed to study the effect of consuming sesame seeds on some biochemical factors in type 2 diabetic patients.
Materials & Methods: This clinical trial has been carried out on 60 type 2 diabetic patients who were randomly divided into two groups of 30 sesame seeds consumers (case) and 30 non sesame seeds consumers (control).The case group was given 60 grams sesame seeds per day for 2 months and the control group did not receive any sesame seeds. The patient information was collected by questionnaire. The fasting blood serum of patients at the beginning and the end of the testing were collected and the biochemical factors of this study were measured in laboratory. For the data analysis, two independent samples t-test and paired t-test were used.
Results: In this study, the mean ± SD (Standard Deviation) of the patients’ ages in the two groups, sesame seeds consumers (case) and non sesame seeds consumers (control), was 72/5 ± 40/52 and 11/6 ± 00/56 years, respectively. The results showed that fasting blood glucose, HbA1C, cholesterol, triglycerides, LDL (Low-density Lipoprotein), ALT (Alanine Transaminase) and ALP (Alkaline Phosphatase) were statistically decreased after the consumption of sesame seeds (P<0.05).
Conclusion: According to the results, and by considering the sesame seeds harmless effects, it can be suggested that probably this plant is useful as a complementary therapy for treatment and prevention of diabetes disorders.

Keywords: Sesame seeds, Type 2 diabetes, Biochemical factors
Full-Text [PDF 880 kb]   (918 Downloads)    
Type of Study: Research | Subject: Biochemistry
Received: 2015/10/4 | Accepted: 2016/02/4 | Published: 2016/06/17
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Ghoreishi A S, Mohammadian Shahrbabaki F, Toghroli N, Sheikh Fathollahi M, Hajizadeh M R, Khoshdel A et al . Investigating the Effect of Sesamum Indicum Consumption on Biochemichal Parameters in Type 2 Diabetic Patients. J Fasa Univ Med Sci. 2016; 6 (1) :87-95
URL: http://journal.fums.ac.ir/article-1-897-en.html
Volume 6, Number 1 (Spring 2016) Back to browse issues page
Journal of Fasa University of Medical Sciences
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