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:: Volume 6, Number 2 (Summer 2016) ::
J Fasa Univ Med Sci 2016, 6(2): 133-137 Back to browse issues page
A Case Report of Suicide with Chloroquine Overdose and Review of Literature
Maryam Hosseini1, Reza Khoshnoud1, Saeed Gholamzadeh 2, Gholamreza Naseri1, Tahereh Tarian1, Abdorrasoul Malekpour1, Mohammad Zarenejad3
1- Researcher Legal Medicine Research Center, Legal Medicine Organization of Iran, Tehran, Iran
2- Researcher Legal Medicine Research Center, Legal Medicine Organization of Iran, Tehran, Iran , saeedghmail@yahoo.com
3- Legal Medicine Research Center, Legal Medicine Organization of Iran, Tehran, Iran
Abstract:   (3357 Views)

Background & Objective: Suicide is considered as the tenth cause of death worldwide. There are several suicide reports consist in the use of certain unusual drugs, such as chloroquine.

Case report: The cadaver of a 25-year-old single woman was found dead in her home and with suspect to using toxins or drugs was brought to Fars Province Forensic administration. She had history of psychiatric problems for which had referred to psychologist several times.

Results: After the autopsy, there was no observation of pathologic lesions in her samples of liver, kidney, or heart. In bile samples, using Thin Layer Chromatography (TLC) and High Performance Liquid Chromatography (HPLC) methods, chloroquine was detected. In visceral and gut samples, chloroquine was found using TLC as +4 reactions and it was confirmed by HPLC and Gas Chromatography Mass Spectrometry (GC-MS). After examining all the aspects, eventually chloroquine overdose and its complications was determined as the cause of the death.

Conclusion: Due to the high incidence of suicide in depressed patients and according to family and previous positive experience, preventive strategies based on the recognition and the treatment of depressed patients and also teaching the families to diagnose the illness in addition to the limitation of the free access to chloroquine and similar drugs is suggested to reduce overdose complications or suicide.

Keywords: Suicide, chloroquine, Depressed patients
Full-Text [PDF 826 kb]   (1462 Downloads)    
Type of Study: case report | Subject: Forensic Medicine
Received: 2016/01/7 | Accepted: 2016/05/14 | Published: 2016/09/10
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Hosseini M, Khoshnoud R, Gholamzadeh S, Naseri G, Tarian T, Malekpour A et al . A Case Report of Suicide with Chloroquine Overdose and Review of Literature. J Fasa Univ Med Sci. 2016; 6 (2) :133-137
URL: http://journal.fums.ac.ir/article-1-980-en.html
Volume 6, Number 2 (Summer 2016) Back to browse issues page
Journal of Fasa University of Medical Sciences
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