Journal of Advanced Biomedical Sciences
JABS
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Volume 3, Issue 3 (9-2013)
JABS 2013, 3(3): 280-284 |
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mozafar A, keshavarz M, zareian P, Johary H, kargar jahromy H, Hoseini S. The effect of immobilization stress on the HPG axis (hypothalamic - pituitary - gonad) hormones and the number of spermatogonia. JABS 2013; 3 (3) :280-284
URL: http://jabs.fums.ac.ir/article-1-225-en.html
URL: http://jabs.fums.ac.ir/article-1-225-en.html
Ahmad Mozafar *1 
, Mojtaba Keshavarz2 , Parvin Zareian3 , Habiboalah Johary4 , Hossein Kargar jahromy5 , Shirzad Hoseini6
, Mojtaba Keshavarz2 , Parvin Zareian3 , Habiboalah Johary4 , Hossein Kargar jahromy5 , Shirzad Hoseini6
1- Department of biology, Islamic Azad University, Jahrom, Fars, Iran. , ahmadmozafar77@yahoo.com
2- Department of biology, Islamic Azad University, Jahrom, Fars, Iran.Young Researcher club Elite, Shiraz branch, Islamic Azad University, Shiraz, Iran.
3- Physiology Department, AJA University of Medical Sciences, Tehran, Iran.
4- Biology Department, Darab Azad University, Darab, Iran.
5- Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran
6- Intensive Care Nurse, fatemeh (P.B.U.H) School of Nursing and Midwifery Shiraz University of Medical Sciences, Shiraz, Iran
2- Department of biology, Islamic Azad University, Jahrom, Fars, Iran.Young Researcher club Elite, Shiraz branch, Islamic Azad University, Shiraz, Iran.
3- Physiology Department, AJA University of Medical Sciences, Tehran, Iran.
4- Biology Department, Darab Azad University, Darab, Iran.
5- Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran
6- Intensive Care Nurse, fatemeh (P.B.U.H) School of Nursing and Midwifery Shiraz University of Medical Sciences, Shiraz, Iran
Abstract: (30143 Views)
Background & Objective: Stress has different effects on the living organisms. In this study the effect of immobilization stress the HPG (hypothalamic - pituitary - gonad axis) hormones secretion and the number of spermatogonia was studied in adult male rats
Materials & Methods: 30 male rats were divided into 3 groups. The Control group: who were not exposed to any kind of stress, and two experimental 7 and 14 day groups which respectively received 2 hours of immobilized stress over 7 and 14 day stress periods, blood samples were collected directly from the heart of the animals, Hormones GnRH, LH and testosterone levels were measured by ELISA. The number of spermatogonia in the testes of adult male rats were counted. We used ANOVA and Duncan's test results in p ≤0.05 for statistic analyze test.
Results: The results showed that immobilization stress significantly decreased concentrations of GnRH and testosterone hormones compared with the control group. Also the 14-day immobilization stress caused a significant reduction in spermatogonia cells.
Conclusion: The results of this study indicate that the inhibitory effect of immobilization stress on the HPG axis may also cause negative effects on the spermatogenesis process.
Type of Study: Research |
Subject:
Physiology
Received: 2013/06/3 | Accepted: 2013/08/15 | Published: 2013/09/23
Received: 2013/06/3 | Accepted: 2013/08/15 | Published: 2013/09/23
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This work is licensed under a Creative Commons — Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)