[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Submit :: Indexing :: Contact Us ::
:: Volume 11, Issue 2 (Summer 2021) ::
JABS 2021, 11(2): 3791-3814 Back to browse issues page
Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers
Farnaz Fattahi 1, Tahereh Zamani2
1- Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran , fattahi_farnaz@yahoo.com
2- The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
Abstract:   (1070 Views)
Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid)(PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.
Keywords: Poly (Lactic Acid), Polymeric Nanoparticle, Cancer Treatment, Drug Deliver, Gene Delivery, Tumor Cell
Full-Text [PDF 320 kb]   (199 Downloads)    
Type of Study: Review | Subject: Nanomedicine
Received: 2020/07/10 | Accepted: 2021/02/27 | Published: 2021/10/6
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Fattahi F, Zamani T. Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers. JABS. 2021; 11 (2) :3791-3814
URL: http://jabs.fums.ac.ir/article-1-2379-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 11, Issue 2 (Summer 2021) Back to browse issues page
Journal of Advanced Biomedical Sciences
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4419