Volume 6, Issue 3 (11-2016)                   JABS 2016, 6(3): 373-379 | Back to browse issues page

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Kazemi A, Kermani J, Rahmati M. The Chronic Effect of Endurance Training On Jip3 Gene Expression in Soleus Muscle of Male Wistar Rats. JABS 2016; 6 (3) :373-379
URL: http://jabs.fums.ac.ir/article-1-864-en.html
The Chronic Effect of Endurance Training On Jip3 Gene Expression in Soleus Muscle of Male Wistar Rats
Abdolreza Kazemi *1 , Jamileh Kermani2 , Masoud Rahmati3
1- Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran , rkazemi22@yahoo.com
2- Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
3- Department of Physical Education, Faculty of Literature & Humanities, Lorestan University, Khoramabad, Iran
Abstract:   (8142 Views)

Background & Objective: Adaptations in neuromuscular system are due to changes in the expression and activity of proteins and its transmitters. JIP 3 protein plays a role in the regulation of structure and function of neurons as well as the establishment of multi-nuclear muscle cells. Considering the effects of exercise on neuromuscular system, the present study aimed to investigate the effects of 6 weeks of endurance training on JIP3 gene expression in soleus muscle of male Wistar rats.

Material & Methods: Ten Wistar male rats were randomly assigned in two groups: trained and control. Endurance training protocol was performed for 6 weeks. Forty eight hours after final training session, the rats were dissected, and soleus muscle was removed. JIP3 gene expression was performed through Real Time PCR method.

Results: Endurance training increased JIP3 gene expression significantly compared to the control group.

Conclusion: It appears that a period of endurance training increases intramuscular gene expression of JIP3 through this can lead to a better consistency and functionality in the muscles.

Keywords: Gene Expression, Endurance Training, JIP3
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Type of Study: Research | Subject: Physiology
Received: 2015/10/14 | Accepted: 2016/07/15 | Published: 2016/12/3
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